Just thought I'd point out a couple of these posts to tide you over, as I won't be able to post for a while.
Question about Runic Power Mastery answered.
Question about Chillblains answered.
Finally, for those of you who might have some trouble with rogues, just remember this tip:
Plague strike will reapply blood plague even if a rogue has cloak of shadows up. As soon as you see a rogue cloak, try and land a new plague strike on them asap.
Plague strike, like serpent sting (which can be used by hunters to accomplish the same thing), doesn't roll a spell-based hit check, and thus isn't affected by the 90% resist rate. As long as you don't get parried/dodged, and the strike lands, the dot will be reapplied, preventing them from utilizing a lengthy vanish.